Chamomile evokes images of soothing herbal tea, a sharp yet tangy aroma, and cold winter days, but it’s much more than a beloved tea flavor. For thousands of years, Chamomile, or Matricaria recutita, has been used in Ayurvedic and TCM practices to treat symptoms of anxiety, stress, depression, insomnia, and gastric distress.
While there are different variants of the Chamomile plant, the shared characteristics are the plant-based materials produced by nature’s antidepressant. Apigenin, one of the primary flavonoids of chamomile, has had the most attribution in clinical trials to calming effects in numerous pathologies and has been shown to improve gut motility and other symptoms related to digestive disorders. Its anti-inflammatory, anti-spasmodic, and potential anti-microbial properties have been recently explored in the last decade as a frontrunner option for the natural treatment of IBS and a series of other disorders that result from dysregulation of the HPA axis.
In this article, we will explore the restorative, calming properties of Chamomile, and how it can help you, the patient, feel better.
Chamomile for Stress & Anxiety
Chamomile’s time-honored position as an aid for supporting those with stress and anxiety is not unfounded. Clinical trials indicate that the use of chamomile can aid in balancing feelings of stress, managing cortisol levels in the bloodstream, and assists in sleep regulation (a critical part of modulating the nervous system’s exposure to excitant molecules).
The effects of chamomile on stress and anxiety are well documented, and the breadth of clinical review and literature discussing its therapeutic role are used as the basis for implementation in conventional medical settings. The primary flavonoid apigenin targets a number of different GABA pathways in the brain, encouraging a sense of calm and exerting an inhibitory effect on neurons responsible for increasing heart rate, certain hormones responsible for exciting the system against potential threats, and even increasing inflammation. This makes chamomile especially helpful for those navigating chronic stress or daily anxiety. Chamomile may also help reduce cortisol levels, the body’s primary stress hormone, contributing to better emotional balance.
Read more about chamomile’s effects on cortisol and its role in natural alternative treatments for anxiety.
Chamomile for Better Sleep
Chamomile has long been used as a natural sleep aid. Its calming properties, largely attributed to apigenin, help bind to receptors in the brain that promote relaxation and drowsiness. Drinking chamomile tea before bed is a time-honored tradition for individuals struggling with insomnia or restlessness.
In a recent 2024 study, apigenin, the primary flavonoid of chamomile, was found to bind to intracellular components indicated in the energy maintenance pathway. Binding to specific coenzymes led to a decrease in the ability of the body to become stimulated, and overall led to a sedative effect. This study positions chamomile as a powerful agent capable of inducing better sleep.
It is essential to note for patients of IBS and other digestive disorders that sleep is critical for proper regulation of the HPA axis. The HPA axis, more informally known as the ‘brain-gut’ axis, is responsible for the proper function of digestion, and stress negatively impacts the functionality of this system. Since sleep directly impacts stress levels, it is important to support your sleep in the best manner possible to manage uncomfortable symptoms. Exhale, Evinature’s supplement containing Chamomile, balances sleep and supports IBS patients as they navigate sleep and stressful situations.
Explore more natural approaches to sleep in our article on Chinese medicine for better sleep.
Chamomile for Digestive Health & Stomach Cramps
Chamomile is commonly used to relieve stomach discomfort, including bloating, cramps, and indigestion. Its antispasmodic and anti-inflammatory effects help relax intestinal muscles and reduce inflammation in the digestive tract.
In IBS, much of the abdominal pains and cramping result from dysfunctional movements of the intestines. Movement of food and materials through the GI tract is primarily accomplished by wave-like motions called peristalsis, but when the movements do not follow a regulated pattern, or the motor neurons connected to the muscles of the intestine fire erratically (as a result of increased stress), this can lead to intensification as the body tries harder to move the material to its final destination, a condition called spastic colon.
Chamomile soothes the HPA axis, reducing the firing of these neurons to a more sedate pattern. In turn, this reduces the intensity of these spasms and leads to a decrease in bloating, cramping, and other uncomfortable sensations.
Whether consumed as tea or in supplement form, chamomile can be a soothing ally for people dealing with occasional or routine digestive upset.
Learn more in our article on chamomile for gut health, or explore our herbal formula Exhale for natural digestive support.
Side Effects and Dosage
While chamomile is generally safe for most people, it’s important to follow usage guidelines and understand any risks.
Who should not take chamomile:
- Individuals allergic to plants in the daisy family (like ragweed or marigold)
- Pregnant or breastfeeding women (unless under medical supervision)
- People taking anticoagulants or sedatives.
Common side effects may include:
- Mild allergic reactions (itching, skin irritation)
- Drowsiness
- Nausea or dizziness (rare)
Safe daily dosage & precautions:
- For tea: 1–2 cups daily, using 1–2 grams of dried flower heads
- For capsules or supplements: 220–1100 mg per day (standardized extract)
- Always consult your physician before starting any new supplement, especially if you are on medication or managing a chronic condition.
Evinature’s signature Exhale formula is crafted to bring you the sleep aid, gut support, and stress relief chamomile offers, together with Ashwagandha and Mimosa Bark to maximize the benefits and reduce the risks.
Summer Pitocchelli-Schwartzman
