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Chamomile Side Effects: What You Need to Know

  • Herbs & Compounds

Chamomile is a common plant enjoyed for its varied repertoire of use in recipes and teas, as well as its reported calming effect towards sleep. 

The-Benefits-of-Chamomile-for-Cortisol-Levels

There are two main types of chamomile used for these means: German chamomile (Matricaria recutitia) and Roman chamomile (Chamaemelum nobile). German chamomile is more commonly used to reduce the effect of anxiety and restore calm to the body, due to its higher concentration of apigenins and other flavonoids. 

Chamomile is commonly used in supplements, teas, and essential oils for a natural approach against anxiety, insomnia, and some digestive issues such as nausea or vomiting.  

Exhale contains Matricaria recutitia or German chamomile, in a potent mix designed to enhance sleep quality, calm the brain-gut axis for better digestion and less nausea, and reduce the effect anxiety has on the body. 

Common Side Effects of Chamomile 

Chamomile is generally regarded as safe. It is approved for over-the-counter use almost internationally due to its high efficacy and reliable use. However, some people may react poorly to chamomile, oftentimes those with a mild allergy to ragweed (a related plant). 

Side effects of chamomile use can include: 

  • Mild reactions may include nausea, vomiting, dizziness, or drowsiness—especially when taken in large quantities or alongside other sedating substances.
  • Skin irritation can also occur, including eczema flare-ups, eye irritation (from compresses or cosmetics containing chamomile), or contact dermatitis.
  • In rare but serious cases, individuals sensitive to plants in the Asteraceae family (such as ragweed, daisies, chrysanthemums, or marigolds) may experience allergic reactions. These can range from mild skin rashes to anaphylaxis, a severe allergic response requiring immediate medical attention.

Who Should Avoid Chamomile?

While chamomile is often seen as gentle, certain groups should use extra caution or avoid it altogether:

  • Pregnant or nursing individuals: There isn’t enough research to confirm chamomile’s safety during pregnancy or breastfeeding. Some studies suggest it may have mild hormonal or estrogenic effects, so it’s best to avoid it unless approved by a healthcare provider.
  • People with allergies to ragweed, daisies, chrysanthemums, or marigolds: Cross-reactivity is possible due to shared plant proteins.

allergies-chamomile

  • Patients scheduled for surgery: Chamomile may interfere with anesthesia or increase bleeding risk. It’s advised to discontinue use at least two weeks before surgery.
  • Children and infants: Only use chamomile products under pediatric guidance, as reactions can occur even at low doses.

Medication and Supplement Interactions

Chamomile can interact with certain medications and herbal products, altering their effects or increasing side effects:

  • Blood thinners (such as warfarin, aspirin, or NSAIDs) — may increase bleeding risk.
  • Sedatives, antidepressants, and anti-seizure drugs — may cause excessive drowsiness when combined with chamomile.
  • Hormone therapies and birth control pills — some data suggest chamomile might reduce their effectiveness.
  • Other herbal supplements — interactions have been noted with garlic, ginkgo, St. John’s wort, and valerian.

If you take any prescription medications or multiple supplements, it’s best to consult a healthcare provider before adding chamomile to your routine.

How to Use Chamomile Responsibly

To enjoy chamomile safely and effectively:

  • Start small. Begin with a mild tea before trying concentrated extracts or capsules.
  • Avoid high doses or combining multiple chamomile-containing products.
  • Choose high-quality, third-party tested sources to ensure purity and avoid contamination.
  • Consult your healthcare provider before use—especially if you’re pregnant, breastfeeding, taking medication, or managing a chronic condition.

Key Takeaways

Chamomile is one of nature’s most popular calming herbs—specifically German chamomile—for good reason. When used responsibly, it’s generally safe and can offer gentle support for stress, sleep, and digestion.

Still, it’s not completely risk-free. The main concerns include allergies, drowsiness, drug interactions, and uncertain safety during pregnancy. Always talk to your doctor or pharmacist before introducing chamomile into your supplement plan.

Summer-Pitocchelli-Schwartzman
Summer Pitocchelli-Schwartzman

author

Summer Pitocchelli-Schwartzman

DISCLAIMER

This blog is not intended to provide diagnosis, treatment, or medical advice. The content provided is for informational purposes only. Please consult with a physician or healthcare professional regarding any medical or health related diagnosis or treatment options. The claims made regarding specific products in this blog are not approved to diagnose, treat, cure, or prevent disease.

Summer-Pitocchelli-Schwartzman
Summer Pitocchelli-Schwartzman

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Reviewed by Prof. Shomron Ben-Horin M.D.

Co-founder & Chief Medical Officer of Evinature, Chief of the Gastroenterology Department & Director of the Gastro-Immunology Research Laboratory at Sheba Medical Center. Currently a professor of Medicine at Tel Aviv University, Ben-Horin has been the President of the Israel IBD Society, a member of the Scientific Committee of the European Crohn’s & Colitis Organization (ECCO), and an Associate Editor of the Journal of Crohn & Colitis. He is currently a member of the prestigious International Organization of IBD (IOIBD), and a member of the Editorial Board of leading journals, Gut, JCC and APT.

Summer-Pitocchelli-Schwartzman
Summer Pitocchelli-Schwartzman

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