Curcumin is a natural compound found in turmeric and has been the subject of growing scientific interest. Researchers have examined it in a variety of study settings to better understand how it interacts with biological processes and how participants report their experiences while using it.
The summaries that follow provide a simple overview of what investigators reported in their published work.
Clinical trials involving Curcumin
The summaries that follow provide a simple overview of what investigators reported in their published work.
A multi-center, randomized, placebo-controlled trial published in Clinical Gastroenterology and Hepatology in 2015, evaluated curcumin taken alongside mesalamine.
Researchers monitored participant assessment, scoring tools, and endoscopic assessments over several weeks.
Curcumin Maintenance Study — Double-Blind, Multicenter Trial
This double-blind trial examined curcumin taken in addition to standard routines.
Researchers tracked symptom scoring, quality-of-life surveys, and laboratory indicators associated with systemic processes such as hs-CRP and ESR.
Curcumin Supplementation — Clinical Outcomes & Biological Markers
A randomized, double-blind study evaluated curcumin paired with standard therapy over eight weeks.
Reported observations included changes in clinical scoring tools, participant surveys, and laboratory measurements such as hs-CRP, ESR, and TNF-α.
Bio-Enhanced Curcumin Add-On Study — Randomized Pilot Trial
A pilot randomized trial assessed a bio-enhanced curcumin (BEC) formula alongside mesalamine.
Researchers recorded clinical scoring changes, endoscopic evaluations, and follow-up observations at 6 and 12 months.
The publication also discussed tolerability and continuation rates.
Curcumin as a Maintenance Approach — Randomized Double-Blind Trial
A multicenter study examined curcumin taken twice daily over six months, followed by six months of observation.
Researchers documented relapse rates, clinical scoring patterns, and endoscopic evaluations.
Comparison of Remicade® and Curcumin — Systematic Review
A systematic review analyzed published research on how curcumin has been examined as a complementary botanical compound in adults receiving infliximab therapy.
Reported findings included the analysis of biological markers such as IL-1, CRP, and TNF-α and trends in clinical scoring tools across studies.
Dietary Antioxidants for Everyday Gut Support — Insights from a Systematic Review and Meta Analysis
A meta-analysis evaluated randomized controlled trials on dietary antioxidants, with curcumin being the only compound that met inclusion criteria.
The review summarized trends in participant-reported outcomes, endoscopic scoring, and quality-of-life survey data across multiple trials.